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Infliximab therapy balances regulatory T cells, tumour necrosis factor receptor 2 (TNFR2) expression and soluble TNFR2 in sarcoidosis

Sarcoidosis is a systemic granulomatous disease of unknown aetiology that most commonly affects the lungs. Although elevated levels of regulatory T cells (T(regs)) have been reported, the extent to which they play a role in sarcoidosis pathogenesis remains unclear. Tumour necrosis factor (TNF) is th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Exp Immunol
Hauptverfasser: Verwoerd, A., Hijdra, D., Vorselaars, A. D. M., Crommelin, H. A., van Moorsel, C. H. M., Grutters, J. C., Claessen, A. M. E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955009/
https://ncbi.nlm.nih.gov/pubmed/27158798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12808
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