Latent cytomegalovirus infection enhances anti‐tumour cytotoxicity through accumulation of NKG2C+ NK cells in healthy humans

Cytomegalovirus (CMV) infection markedly expands NKG2C+/NKG2A− NK cells, which are potent killers of infected cells expressing human leucocyte antigen (HLA)‐E. As HLA‐E is also over‐expressed in several haematological malignancies and CMV has been linked to a reduced risk of leukaemic relapse, we de...

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Publicado en:Clin Exp Immunol
Autores principales: Bigley, A. B., Rezvani, K., Shah, N., Sekine, T., Balneger, N., Pistillo, M., Agha, N., Kunz, H., O'Connor, D. P., Bollard, C. M., Simpson, R. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955006/
https://ncbi.nlm.nih.gov/pubmed/26940026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12785
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