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Analysis of peginterferon β-1a exposure and Gd-enhanced lesion or T2 lesion response in relapsing-remitting multiple sclerosis patients

The effect of subcutaneous (SC) peginterferon β-1a exposure on reduction of gadolinium-enhanced (Gd+) lesion count over time was evaluated in patients with relapsing-remitting multiple sclerosis (RRMS) in a Phase 3 study (ADVANCE). Patients were randomized to receive SC injections of placebo (n = 50...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Pharmacokinet Pharmacodyn
Hauptverfasser: Hang, Yaming, Hu, Xiao, Zhang, Jie, Liu, Shifang, Deykin, Aaron, Nestorov, Ivan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954841/
https://ncbi.nlm.nih.gov/pubmed/27299457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-016-9477-x
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