Pyridoxine Supplementation Improves the Activity of Recombinant Glutamate Decarboxylase and the Enzymatic Production of Gama-Aminobutyric Acid

Glutamate decarboxylase (GAD) catalyzes the irreversible decarboxylation of L-glutamate to the valuable food supplement γ-aminobutyric acid (GABA). In this study, GAD from Escherichia coli K12, a pyridoxal phosphate (PLP)-dependent enzyme, was overexpressed in E. coli. The GAD produced in media supp...

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Udgivet i:PLoS One
Main Authors: Huang, Yan, Su, Lingqia, Wu, Jing
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954698/
https://ncbi.nlm.nih.gov/pubmed/27438707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157466
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