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The involvement of mutant Rac1 in the formation of invadopodia in cultured melanoma cells

In this article, we discuss the complex involvement of a Rho-family GTPase, Rac1, in cell migration and in invadopodia-mediated matrix degradation. We discuss the involvement of invadopodia in invasive cell migration, and their capacity to promote cancer metastasis. Considering the regulation of inv...

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Bibliographic Details
Published in:Exp Cell Res
Main Authors: Revach, Or-Yam, Winograd-Katz, Sabina E, Samuels, Yardena, Geiger, Benjamin
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954600/
https://ncbi.nlm.nih.gov/pubmed/26873115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2016.02.003
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