Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells

Pluripotent stem cells offer great therapeutic promise for personalized treatment platforms for numerous injuries, disorders, and diseases. Octamer-binding transcription factor 4 (OCT4) is a key regulatory gene maintaining pluripotency and self-renewal of mammalian cells. With site-specific integrat...

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Publicat a:Mol Ther Methods Clin Dev
Autors principals: Vega-Crespo, Agustin, Truong, Brian, Hermann, Kip J, Awe, Jason P, Chang, Katherine M, Lee, Patrick C, Schoenberg, Benjamen E, Wu, Lily, Byrne, James A, Lipshutz, Gerald S
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954563/
https://ncbi.nlm.nih.gov/pubmed/27500178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.50
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