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Adapting Preclinical Benchmarks for First-in-Human Trials of Human Embryonic Stem Cell-Based Therapies

As research on human embryonic stem cell (hESC)-based therapies is moving from the laboratory to the clinic, there is an urgent need to assess when it can be ethically justified to make the step from preclinical studies to the first protocols involving human subjects. We examined existing regulatory...

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Pubblicato in:Stem Cells Transl Med
Autori principali: Barazzetti, Gaia, Hurst, Samia A., Mauron, Alexandre
Natura: Artigo
Lingua:Inglês
Pubblicazione: AlphaMed Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954447/
https://ncbi.nlm.nih.gov/pubmed/27334488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0222
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