Treatment With Human Wharton’s Jelly-Derived Mesenchymal Stem Cells Attenuates Sepsis-Induced Kidney Injury, Liver Injury, and Endothelial Dysfunction

The pathophysiology of sepsis involves complex cytokine and inflammatory mediator networks. Downregulation of endothelial nitric oxide synthase contributes to sepsis-induced endothelial dysfunction. Human Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) are known to reduce expression of proi...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Cóndor, José M., Rodrigues, Camila E., de Sousa Moreira, Roberto, Canale, Daniele, Volpini, Rildo A., Shimizu, Maria H.M., Camara, Niels O.S., Noronha, Irene de L., Andrade, Lúcia
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2016
Assuntos:
Enabling Technologies for Cell-Based Clinical Translation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954445/
https://ncbi.nlm.nih.gov/pubmed/27280799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0138
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