Antibody blockade of IL-17 family cytokines in immunity to acute murine oral mucosal candidiasis

Antibodies targeting IL-17A or its receptor, IL-17RA, are approved to treat psoriasis and are being evaluated for other autoimmune conditions. Conversely, IL-17 signaling is critical for immunity to opportunistic mucosal infections caused by the commensal fungus Candida albicans, as mice and humans...

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Veröffentlicht in:J Leukoc Biol
Hauptverfasser: Whibley, Natasha, Tritto, Elaine, Traggiai, Elisabetta, Kolbinger, Frank, Moulin, Pierre, Brees, Dominique, Coleman, Bianca M., Mamo, Anna J., Garg, Abhishek V., Jaycox, Jillian R., Siebenlist, Ulrich, Kammüller, Michael, Gaffen, Sarah L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Leukocyte Biology 2016
Schlagworte:
Host Defense & Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4952011/
https://ncbi.nlm.nih.gov/pubmed/26729813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4A0915-428R
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