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Role of lysophosphatidylcholine in T-lymphocyte activation: involvement of phospholipase A2 in signal transduction through protein kinase C.

2-Lysophosphatidylcholine (lysoPtdCho), a product of the hydrolysis of phosphatidylcholine catalyzed by phospholipase A2, greatly potentiates the activation of human resting T lymphocytes that is induced by a membrane-permeant diacylglycerol plus a calcium ionophore, as determined by the expression...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Asaoka, Y, Oka, M, Yoshida, K, Sasaki, Y, Nishizuka, Y
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49518/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631142/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6447
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