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Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways, and up-regulates GABA(A) receptor expression and CREB1 activity in rats
Aripiprazole is a D(2)-like receptor (D(2)R) partial agonist with a favourable clinical profile. Previous investigations indicated that acute and short-term administration of aripiprazole had effects on PKA activity, GSK3β-dependent pathways, GABA(A) receptors, NMDA receptor and CREB1 in the brain....
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| Publicado no: | Sci Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4951756/ https://ncbi.nlm.nih.gov/pubmed/27435909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30040 |
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