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Promotion of axon regeneration and inhibition of astrocyte activation by alpha A-crystallin on crushed optic nerve

AIM: To explore the effects of αA-crystallin in astrocyte gliosis after optic nerve crush (ONC) and the mechanism of α-crystallin in neuroprotection and axon regeneration. METHODS: ONC was established on the Sprague-Dawley rat model and αA-crystallin (10(−4) g/L, 4 µL) was intravitreously injected i...

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Detalhes bibliográficos
Publicado no:Int J Ophthalmol
Main Authors: Shao, Wei-Yang, Liu, Xiao, Gu, Xian-Liang, Ying, Xi, Wu, Nan, Xu, Hai-Wei, Wang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: International Journal of Ophthalmology Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951673/
https://ncbi.nlm.nih.gov/pubmed/27500100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2016.07.04
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