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Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling

Myelin, which ensheaths and insulates axons, is a specialized membrane highly enriched with cholesterol. During myelin formation, cholesterol influences membrane fluidity, associates with myelin proteins such as myelin proteolipid protein, and assembles lipid-rich microdomains within membranes. Surp...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Mathews, Emily S., Appel, Bruce
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951573/
https://ncbi.nlm.nih.gov/pubmed/27445141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0726-16.2016
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