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Phosphoproteomic Analysis Reveals a Novel Mechanism of CaMKIIα Regulation Inversely Induced by Cocaine Memory Extinction versus Reconsolidation

Successful addiction treatment depends on maintaining long-term abstinence, making relapse prevention an essential therapeutic goal. However, exposure to environmental cues associated with drug use often thwarts abstinence efforts by triggering drug using memories that drive craving and relapse. We...

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Vydáno v:J Neurosci
Hlavní autoři: Rich, Matthew T., Abbott, Thomas B., Chung, Lisa, Gulcicek, Erol E., Stone, Kathryn L., Colangelo, Christopher M., Lam, TuKiet T., Nairn, Angus C., Taylor, Jane R., Torregrossa, Mary M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951572/
https://ncbi.nlm.nih.gov/pubmed/27445140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1108-16.2016
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