Multilevel Precision-Based Rational Design of Chemical Inhibitors Targeting the Hydrophobic Cleft of Toxoplasma gondii Apical Membrane Antigen 1 (AMA1)

Toxoplasma gondii is an intracellular Apicomplexan parasite and a causative agent of toxoplasmosis in human. It causes encephalitis, uveitis, chorioretinitis, and congenital infection. T. gondii invades the host cell by forming a moving junction (MJ) complex. This complex formation is initiated by i...

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Detalhes bibliográficos
Publicado no:Genomics Inform
Main Authors: Vetrivel, Umashankar, Muralikumar, Shalini, Mahalakshmi, B, Lily Therese, K, Madhavan, HN, Alameen, Mohamed, Thirumudi, Indhuja
Formato: Artigo
Idioma:Inglês
Publicado em: Korea Genome Organization 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951401/
https://ncbi.nlm.nih.gov/pubmed/27445648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5808/GI.2016.14.2.53
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