Methylation-associated silencing of miR-200b facilitates human hepatocellular carcinoma progression by directly targeting BMI1

This study aims to investigate the biological function of microRNA-200b and BMI1, predicted target of microRNA-200b in human hepatocellular carcinoma (HCC). MicroRNA-200b and BMI1 expression in HCC tissues were evaluated by qPCR. A luciferase reporter assay was used to validate BMI1 as a direct targ...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Wu, Wen-rui, Sun, Hong, Zhang, Rui, Yu, Xian-huan, Shi, Xiang-de, Zhu, Man-sheng, Zeng, Hong, Yan, Li-xu, Xu, Lei-bo, Liu, Chao
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951320/
https://ncbi.nlm.nih.gov/pubmed/26919246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7629
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