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Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling

Esophageal cancer is one of the most common malignancies worldwide. DACT2 is frequently methylated in human lung, hepatic, gastric and thyroid cancers. The methylation status and function of DACT2 remain to be elucidated in human esophageal cancer. Ten esophageal cancer cell lines, 42 cases of dyspl...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Zhang, Meiying, Linghu, Enqiang, Zhan, Qimin, He, Tao, Cao, Baoping, Brock, Malcolm V., Herman, James G., Xiang, Rong, Guo, Mingzhou
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951263/
https://ncbi.nlm.nih.gov/pubmed/26919254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7647
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