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DDRI-9: a novel DNA damage response inhibitor that blocks mitotic progression

The DNA damage response (DDR) is an emerging target for cancer therapy. By modulating the DDR, including DNA repair and cell cycle arrest, the efficacy of anticancer drugs can be enhanced and side effects reduced. We previously screened a chemical library and identified novel DDR inhibitors includin...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jun, Dong Wha, Hwang, Mihwa, Kim, Yun-Hee, Kim, Kyung-Tae, Kim, Sunshin, Lee, Chang-Hun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951243/
https://ncbi.nlm.nih.gov/pubmed/26848527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7135
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