A human anti-polysialic acid antibody as a potential treatment to improve function in multiple sclerosis patients

We previously identified a human monoclonal antibody, termed HIgM12 that stimulates spontaneous locomotor activity in a chronically demyelinating mouse model of multiple sclerosis. When tested as a molecular substrate, HIgM12 stimulated neurite outgrowth in vitro. We recently reported that polysiali...

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Vydáno v:J Nat Sci
Hlavní autoři: Watzlawik, Jens O., Painter, Meghan M., Wootla, Bharath, Rodriguez, Moses
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951103/
https://ncbi.nlm.nih.gov/pubmed/27446988
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