Fasudil inhibits LPS-induced migration of retinal microglial cells via regulating p38-MAPK signaling pathway

PURPOSE: To investigate the effect and possible molecular mechanisms of fasudil on retinal microglial (RMG) cell migration. METHODS: Primary cultured RMG cells were incubated with lipopolysaccharide (LPS), fasudil, and/or SB203580 (a p38 inhibitor). RMG cell motility was determined with the scratch...

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Bibliographic Details
Published in:Mol Vis
Main Authors: Xu, Fan, Xu, Yue, Zhu, Liqiong, Rao, Pinhong, Wen, Jiamin, Sang, Yunyun, Shang, Fu, Liu, Yizhi
Format: Artigo
Language:Inglês
Published: Molecular Vision 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951004/
https://ncbi.nlm.nih.gov/pubmed/27441000
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