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ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein beta-COP to Golgi membranes.

The coatomer is a cytosolic protein complex that reversibly associates with Golgi membranes and is implicated in modulating Golgi membrane transport. The association of beta-COP, a component of coatomer, with Golgi membranes is enhanced by guanosine 5'-[gamma-thio]triphosphate (GTP[gamma S]), a nonh...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Donaldson, J G, Cassel, D, Kahn, R A, Klausner, R D
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1992
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49510/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631136/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6408
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