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Azaindole Synthesis Through Dual Activation Catalysis with N-Heterocyclic Carbenes

A convergent, transition-metal-free synthesis of 2-aryla-zaindoles has been developed. The interception of a reactive aza-ortho-azaquinone methide intermediate by an acyl anion equivalent generated through carbene catalysis provides high yields, a wide substrate scope, and the synthesis of previousl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chem Commun (Camb)
Egile Nagusiak: Sharma, Hayden A., Hovey, M. Todd, Scheidt, Karl A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950954/
https://ncbi.nlm.nih.gov/pubmed/27363788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc04735a
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