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Biomechanical Signals Suppress TAK1 Activation to Inhibit NF-κB Transcriptional Activation in Fibrochondrocytes

Exercise/joint mobilization is therapeutic for inflammatory joint diseases like rheumatoid and osteoarthritis, but the mechanisms underlying its actions remain poorly understood. We report that biomechanical signals at low/physiological magnitudes are potent inhibitors of inflammation induced by div...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Madhavan, Shashi, Anghelina, Mirela, Sjostrom, Danen, Dossumbekova, Anar, Guttridge, Denis C., Agarwal, Sudha
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950928/
https://ncbi.nlm.nih.gov/pubmed/17947700
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