In vitro characterization of neurite extension using induced pluripotent stem cells derived from lissencephaly patients with TUBA1A missense mutations

BACKGROUND: Lissencephaly, or smooth brain, is a severe congenital brain malformation that is thought to be associated with impaired neuronal migration during corticogenesis. However, the exact etiology of lissencephaly in humans remains unknown. Research on congenital diseases is limited by the sho...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Brain
Autori principali: Bamba, Yohei, Shofuda, Tomoko, Kato, Mitsuhiro, Pooh, Ritsuko K., Tateishi, Yoko, Takanashi, Jun-ichi, Utsunomiya, Hidetsuna, Sumida, Miho, Kanematsu, Daisuke, Suemizu, Hiroshi, Higuchi, Yuichiro, Akamatsu, Wado, Gallagher, Denis, Miller, Freda D., Yamasaki, Mami, Kanemura, Yonehiro, Okano, Hideyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950778/
https://ncbi.nlm.nih.gov/pubmed/27431206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0246-y
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi