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p21 induction plays a dual role in anti-cancer activity of ursolic acid
Previous studies have shown that induction of G1 arrest and apoptosis by ursolic acid is associated with up-regulation of cyclin-dependent kinase inhibitor (CDKI) protein p21 in multiple types of cancer cells. However, the functional role of p21 induction in G1 cell cycle arrest and apoptosis, and t...
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| Publicado no: | Exp Biol Med (Maywood) |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4950478/ https://ncbi.nlm.nih.gov/pubmed/26582056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215616195 |
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