Berberine induces dedifferentiation by actin cytoskeleton reorganization via phosphoinositide 3-kinase/Akt and p38 kinase pathways in rabbit articular chondrocytes

Osteoarthritis is a nonrheumatologic joint disease characterized by progressive degeneration of the cartilage extracellular matrix. Berberine (BBR) is an isoquinoline alkaloid used in traditional Chinese medicine, the majority of which is extracted from Huang Lian (Coptis chinensis). Although numero...

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Vydáno v:Exp Biol Med (Maywood)
Hlavní autoři: Yu, Seon-Mi, Cho, Hongsik, Kim, Gwang-Hoon, Chung, Ki-Wha, Seo, Sung-Yum, Kim, Song-Ja
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950397/
https://ncbi.nlm.nih.gov/pubmed/26851252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216631028
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