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Original Research: Use of hydroxyurea and phlebotomy in pediatric patients with hemoglobin SC disease

Hydroxyurea is an excellent therapeutic agent for the pharmacological induction of HbF in patients with sickle cell disease (SCD). However, all completed clinical trials of hydroxyurea have excluded patients with hemoglobin SC (HbSC) disease. HbSC differs significantly in pathophysiology from HbSS,...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Summarell, Carly C Ginter, Sheehan, Vivien A
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950384/
https://ncbi.nlm.nih.gov/pubmed/26993671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216639737
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