Lipidoid nanoparticle mediated silencing of Mcl-1 induces apoptosis in mantle cell lymphoma

Conventional chemo-immunotherapy fails to cure the majority of mantle cell lymphoma patients and causes substantial toxicity. Resistant mantle cell lymphoma cells commonly overexpress and are dependent on the anti-apoptotic protein, Mcl-1, for survival. In this study, we use potent lipidoid nanopart...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Exp Biol Med (Maywood)
Asıl Yazarlar: Knapp, Christopher M, He, Jia, Lister, John, Whitehead, Kathryn A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SAGE Publications 2016
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950348/
https://ncbi.nlm.nih.gov/pubmed/27022142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216640944
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