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Bayesian meta‐analytical methods to incorporate multiple surrogate endpoints in drug development process

A number of meta‐analytical methods have been proposed that aim to evaluate surrogate endpoints. Bivariate meta‐analytical methods can be used to predict the treatment effect for the final outcome from the treatment effect estimate measured on the surrogate endpoint while taking into account the unc...

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Détails bibliographiques
Publié dans:Stat Med
Auteurs principaux: Bujkiewicz, Sylwia, Thompson, John R., Riley, Richard D., Abrams, Keith R.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950070/
https://ncbi.nlm.nih.gov/pubmed/26530518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6776
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