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DNA fingerprints of Helicobacter pylori before and after treatment with omeprazole.

AIMS: To test whether a hypoacidic environment may potentially "stress" Helicobacter pylori DNA, encouraging the emergence of strain variation. METHODS: This hypothesis was tested by inducing prolonged hypoacidity with omeprazole, a potent antisecretory drug. The genomic DNA of H pylori wa...

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Main Authors: Fraser, A G, Bickley, J, Owen, R J, Pounder, R E
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC494997/
https://ncbi.nlm.nih.gov/pubmed/1282520
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