Cell cycle-dependent initiation and lineage-dependent abrogation of GATA-1 expression in pure differentiating hematopoietic progenitors.

The programmed activation/repression of transcription factors in early hematopoietic differentiation has not yet been explored. The DNA-binding protein GATA-1 is required for normal erythroid development and regulates erythroid-expressed genes in maturing erythroblasts. We analyzed GATA-1 expression...

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Autors principals: Sposi, N M, Zon, L I, Carè, A, Valtieri, M, Testa, U, Gabbianelli, M, Mariani, G, Bottero, L, Mather, C, Orkin, S H
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC49499/
https://ncbi.nlm.nih.gov/pubmed/1631130
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