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Mycolic acids: deciphering and targeting the Achilles' heel of the tubercle bacillus

Mycolic acids are unique long chain fatty acids found in the lipid‐rich cell walls of mycobacteria including the tubercle bacillus M ycobacterium tuberculosis. Essential for viability and virulence, enzymes involved in the biosynthesis of mycolic acids represent novel targets for drug development. T...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: Nataraj, Vijayashankar, Varela, Cristian, Javid, Asma, Singh, Albel, Besra, Gurdyal S., Bhatt, Apoorva
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949712/
https://ncbi.nlm.nih.gov/pubmed/26135034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13101
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