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Increased linear bone growth by GH in the absence of SOCS2 is independent of IGF‐1

Growth hormone (GH) signaling is essential for postnatal linear bone growth, but the relative importance of GHs actions on the liver and/or growth plate cartilage remains unclear. The importance of liver derived insulin like‐growth factor‐1 (IGF‐1) for endochondral growth has recently been challenge...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Dobie, Ross, Ahmed, Syed F., Staines, Katherine A., Pass, Chloe, Jasim, Seema, MacRae, Vicky E., Farquharson, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949688/
https://ncbi.nlm.nih.gov/pubmed/25833299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25006
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