Increased linear bone growth by GH in the absence of SOCS2 is independent of IGF‐1

Growth hormone (GH) signaling is essential for postnatal linear bone growth, but the relative importance of GHs actions on the liver and/or growth plate cartilage remains unclear. The importance of liver derived insulin like‐growth factor‐1 (IGF‐1) for endochondral growth has recently been challenge...

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Veröffentlicht in:J Cell Physiol
Hauptverfasser: Dobie, Ross, Ahmed, Syed F., Staines, Katherine A., Pass, Chloe, Jasim, Seema, MacRae, Vicky E., Farquharson, Colin
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
Schlagworte:
Original Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949688/
https://ncbi.nlm.nih.gov/pubmed/25833299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25006
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