Laddar...

Importance of Genetic Studies in Consanguineous Populations for the Characterization of Novel Human Gene Functions

Consanguineous offspring have elevated levels of homozygosity. Autozygous stretches within their genome are likely to harbour loss of function (LoF) mutations which will lead to complete inactivation or dysfunction of genes. Studying consanguineous offspring with clinical phenotypes has been very us...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Ann Hum Genet
Huvudupphovsmän: Erzurumluoglu, A. Mesut, Shihab, Hashem A., Rodriguez, Santiago, Gaunt, Tom R., Day, Ian N.M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949565/
https://ncbi.nlm.nih.gov/pubmed/27000383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12150
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!