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1918 Influenza Receptor Binding Domain Variants Bind and Replicate in Primary Human Airway Cells Regardless of Receptor Specificity
The 1918 influenza pandemic caused ~50 million deaths. Many questions remain regarding the origin, pathogenicity, and mechanisms of human adaptation of this virus. Avian-adapted influenza A viruses preferentially bind α2,3-linked sialic acids (Sia) while human-adapted viruses preferentially bind α2,...
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| Pubblicato in: | Virology |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4949484/ https://ncbi.nlm.nih.gov/pubmed/27062579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.03.025 |
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