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Bile signalling promotes chronic respiratory infections and antibiotic tolerance

Despite aggressive antimicrobial therapy, many respiratory pathogens persist in the lung, underpinning the chronic inflammation and eventual lung decline that are characteristic of respiratory disease. Recently, bile acid aspiration has emerged as a major comorbidity associated with a range of lung...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Reen, F. Jerry, Flynn, Stephanie, Woods, David F., Dunphy, Niall, Chróinín, Muireann Ní, Mullane, David, Stick, Stephen, Adams, Claire, O’Gara, Fergal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949476/
https://ncbi.nlm.nih.gov/pubmed/27432520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29768
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