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Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling

Inheritance depends on the expansion of a small number of primordial germ cells (PGCs) in the early embryo. Proliferation of mammalian PGCs is concurrent with their movement through changing microenvironments; however, mechanisms coordinating these conflicting processes remain unclear. Here, we find...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Cantú, Andrea V., Altshuler-Keylin, Svetlana, Laird, Diana J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949447/
https://ncbi.nlm.nih.gov/pubmed/27402951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201511061
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