Serotonin-Exacerbated DSS-Induced Colitis Is Associated with Increase in MMP-3 and MMP-9 Expression in the Mouse Colon

Background. 5-HT enhances dextran sulfate sodium- (DSS-) induced colitis and is involved in inflammatory bowel disease (IBD). Matrix metalloproteinases (MMPs) play roles in the process of intestinal inflammation. Aims. To examine whether 5-HT induces MMPs expression in mouse colon to enhance DSS-ind...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Chen, Menglu, Gao, Lei, Chen, Pan, Feng, Dandan, Jiang, Yalin, Chang, Yongchao, Jin, Jianjun, Chu, Fong-Fong, Gao, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949340/
https://ncbi.nlm.nih.gov/pubmed/27478308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5359768
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