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The C2H2-ZF transcription factor Zfp335 recognizes two consensus motifs using separate zinc finger arrays

The complexities of DNA recognition by transcription factors (TFs) with multiple Cys2–His2 zinc fingers (C2H2-ZFs) remain poorly studied. We previously reported a mutation (R1092W) in the C2H2-ZF TF Zfp335 that led to selective loss of binding at a subset of targets, although the basis for this effe...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Han, Brenda Yuyuan, Foo, Chuan-Sheng, Wu, Shuang, Cyster, Jason G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949324/
https://ncbi.nlm.nih.gov/pubmed/27401554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.279406.116
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