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Osmotherapy with Hypertonic Saline Attenuates Global Cerebral Edema following Experimental Cardiac Arrest via Perivascular Pool of Aquaporin-4
OBJECTIVE: We tested the hypothesis that osmotherapy with hypertonic saline (HS) attenuates cerebral edema following experimental cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) by exerting its effect via the perivascular pool of aquaporin-4 (AQP4). We used mice with targeted disruption...
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| Publicado en: | Crit Care Med |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4949130/ https://ncbi.nlm.nih.gov/pubmed/27035238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000001671 |
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