Hyperhomocysteinemia exacerbates Alzheimer’s disease pathology by way of the Aβ-fibrinogen interaction

BACKGROUND: Accumulating clinical evidence suggests that hyperhomocysteinemia (HHC) is correlated with Alzheimer’s disease (AD) and vascular dementia. OBJECTIVE: This study was carried out to elucidate the specific role of elevated homocysteine (HC) levels in AD pathophysiology. METHODS: Immunohisto...

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Pubblicato in:J Thromb Haemost
Autori principali: Chung, Young Cheul, Kruyer, Anna, Yao, Yao, Feierman, Emily, Richards, Allison, Strickland, Sidney, Norris, Erin H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949110/
https://ncbi.nlm.nih.gov/pubmed/27090576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13340
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