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Human Phase 1 trial of low-dose inactivated seasonal influenza vaccine formulated with Advax™ delta inulin adjuvant

Influenza vaccines are usually non-adjuvanted but addition of adjuvant may improve immunogenicity and permit dose-sparing, critical for vaccine supply in the event of an influenza pandemic. The aim of this first-in-man study was to determine the effect of delta inulin adjuvant on the safety and immu...

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Détails bibliographiques
Publié dans:Vaccine
Auteurs principaux: Gordon, David L., Sajkov, Dimitar, Honda-Okubo, Yoshikazu, Wilks, Samuel H., Aban, Malet, Barr, Ian G., Petrovsky, Nikolai
Format: Artigo
Langue:Inglês
Publié: Elsevier Ltd. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949042/
https://ncbi.nlm.nih.gov/pubmed/27342914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.05.071
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