Combined Iron Chelator and Antioxidant Exerted Greater Efficacy on Cardioprotection Than Monotherapy in Iron-Overloaded Rats

BACKGROUND: Iron chelators are used to treat iron overload cardiomyopathy patients. However, a direct comparison of the benefits of three common iron chelators (deferoxamine (DFO), deferiprone (DFP) and deferasirox (DFX)) or an antioxidant (N-acetyl cysteine (NAC)) with a combined DFP and NAC treatm...

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Veröffentlicht in:PLoS One
Hauptverfasser: Wongjaikam, Suwakon, Kumfu, Sirinart, Khamseekaew, Juthamas, Sripetchwandee, Jirapas, Srichairatanakool, Somdet, Fucharoen, Suthat, Chattipakorn, Siriporn C., Chattipakorn, Nipon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948821/
https://ncbi.nlm.nih.gov/pubmed/27428732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159414
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