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Effect of a controlled-release drug delivery system made of oleanolic acid formulated into multivesicular liposomes on hepatocellular carcinoma in vitro and in vivo

The aim of the present study was to develop a novel dosage form of multivesicular liposomes for oleanolic acid (OA) to overcome its poor solubility, prolong therapeutic drug levels in the blood, and enhance the antitumor effect on hepatocellular carcinoma. OA-encapsulated multivesicular liposomes (O...

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Bibliografski detalji
Izdano u:Int J Nanomedicine
Glavni autori: Luo, Yuling, Liu, Zhongbing, Zhang, Xiaoqin, Huang, Juan, Yu, Xin, Li, Jinwei, Xiong, Dan, Sun, Xiaoduan, Zhong, Zhirong
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2016
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948731/
https://ncbi.nlm.nih.gov/pubmed/27471381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S108445
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