Simvastatin attenuates radiation-induced salivary gland dysfunction in mice

OBJECTIVE: Statins are widely used lipid-lowering drugs, which have pleiotropic effects, such as anti-inflammation, and vascular protection. In our study, we investigated the radioprotective potential of simvastatin (SIM) in a murine model of radiation-induced salivary gland dysfunction. DESIGN: Nin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Des Devel Ther
Main Authors: Xu, Liping, Yang, Xi, Chen, Jiayan, Ge, Xiaolin, Qin, Qin, Zhu, Hongcheng, Zhang, Chi, Sun, Xinchen
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2016
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948692/
https://ncbi.nlm.nih.gov/pubmed/27471375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S105809
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