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Sequence-Dependent Conformational Heterogeneity and Proton-Transfer Reactivity of the Fluorescent Guanine Analogue 6-Methyl Isoxanthopterin (6-MI) in DNA

The local conformations of individual nucleic acid bases in DNA are important components in processes fundamental to gene regulation. Fluorescent nucleic acid base analogues, which can be substituted for natural bases in DNA, can serve as useful spectroscopic probes of average local base conformatio...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Johnson, Neil P., Ji, Huiying, Steinberg, Thomas H., von Hippel, Peter H., Marcus, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948594/
https://ncbi.nlm.nih.gov/pubmed/26368400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b06361
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