Gene targeting of the transcription factor Mohawk in rats causes heterotopic ossification of Achilles tendon via failed tenogenesis

Cell-based or pharmacological approaches for promoting tendon repair are currently not available because the molecular mechanisms of tendon development and healing are not well understood. Although analysis of knockout mice provides many critical insights, small animals such as mice have some limita...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Suzuki, Hidetsugu, Ito, Yoshiaki, Shinohara, Masahiro, Yamashita, Satoshi, Ichinose, Shizuko, Kishida, Akio, Oyaizu, Takuya, Kayama, Tomohiro, Nakamichi, Ryo, Koda, Naoki, Yagishita, Kazuyoshi, Lotz, Martin K., Okawa, Atsushi, Asahara, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948356/
https://ncbi.nlm.nih.gov/pubmed/27370800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522054113
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