Inhibition of human immunodeficiency virus activity by phosphorodithioate oligodeoxycytidine.

Phosphorothioate oligodeoxynucleotides exert a sequence-independent cytoprotective effect against human immunodeficiency virus type 1 (HIV-1). We now report that phosphorodithioate-containing oligodeoxycytidines are very potent inhibitors of HIV-1 reverse transcriptase in vitro, as they exhibit an i...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Marshall, W S, Beaton, G, Stein, C A, Matsukura, M, Caruthers, M H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49481/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1378623/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6265
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