Nanotherapy silencing the interleukin‐8 gene produces regression of prostate cancer by inhibition of angiogenesis

Interleukin‐8 (IL‐8) is a pro‐angiogenic cytokine associated with aggressive prostate cancer (CaP). We detected high levels of IL‐8 in sera from patients with CaP compared with healthy controls and patients with benign prostatic hypertrophy. This study examines the role of IL‐8 in the pathogenesis o...

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Veröffentlicht in:Immunology
Hauptverfasser: Aalinkeel, Ravikumar, Nair, Bindukumar, Chen, Chih‐Kuang, Mahajan, Supriya D., Reynolds, Jessica L., Zhang, Hanguang, Sun, Haotian, Sykes, Donald E., Chadha, Kailash C., Turowski, Steven G., Bothwell, Katelyn D., Seshadri, Mukund, Cheng, Chong, Schwartz, Stanley A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948039/
https://ncbi.nlm.nih.gov/pubmed/27159450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12618
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