Analysis of the function of IL-10 in chickens using specific neutralising antibodies and a sensitive capture ELISA

In mammals, the inducible cytokine interleukin 10 is a feedback negative regulator of inflammation. To determine the extent to which this function is conserved in birds, recombinant chicken IL-10 was expressed as a secreted human Ig Fc fusion protein (chIL-10-Fc) and used to immunise mice. Five mono...

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Publicado en:Dev Comp Immunol
Main Authors: Wu, Zhiguang, Hu, Tuanjun, Rothwell, Lisa, Vervelde, Lonneke, Kaiser, Pete, Boulton, Kay, Nolan, Matthew J., Tomley, Fiona M., Blake, Damer P., Hume, David A.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Science 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947970/
https://ncbi.nlm.nih.gov/pubmed/27108075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dci.2016.04.016
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